Mid-stage OA lacks effective treatments
Traditionally, mid-stage osteoarthritis has been treated with hyaluronic acid (HA) viscosupplements injected into the joint to try to improve the viscosity of the synovial fluid and reduce pain and swelling within the joint. However, injected HA only stays in the joint for 1-2 days and often is ineffective. Some trials have shown no superior benefit when compared to placebo.
